The synthesis of low-molecular weight proteoglycans in rabbit-ear cartilage
نویسندگان
چکیده
منابع مشابه
comparison of catalytic activity of heteropoly compounds in the synthesis of bis(indolyl)alkanes.
heteropoly acids (hpa) and their salts have advantages as catalysts which make them both economically and environmentally attractive, strong br?nsted acidity, exhibiting fast reversible multi-electron redox transformations under rather mild conditions, very high solubility in polar solvents, fairly high thermal stability in the solid states, and efficient oxidizing ability, so that they are imp...
15 صفحه اولCartilage proteoglycans.
The predominant proteoglycan present in cartilage is the large chondroitin sulfate proteoglycan 'aggrecan'. Following its secretion, aggrecan self-assembles into a supramolecular structure with as many as 50 monomers bound to a filament of hyaluronan. Aggrecan serves a direct, primary role providing the osmotic resistance necessary for cartilage to resist compressive loads. Other proteoglycans ...
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Proteoglycan monomers from guinea-pig costal cartilage, bovine nasal and bovine tracheal cartilage were observed in the electron microscope after being spread in a monomolecular layer with cytochrome c. The proteoglycan molecule appeared as an extended central core filament to which side-chain filaments were attached at various intervals. The molecules from the three sources displayed great ult...
متن کاملProteoglycans: their structure, interactions and molecular organization in cartilage.
The term ‘proteoglycan’ was introduced in 1967 (see Balazs. 1970) to describe the family of molecules in which glycosaminoglycan chains are linked to protein. However. their rate of diffusion into textbooks of biochemistry has been rather slow, and I will therefore begin this presentation with a general introduction, which I hope will set the basis for their structural identity and indicate how...
متن کاملProteoglycans of cartilage.
Proteoglycans are probably the most important nonfibrillar constituents of connective tissue although little is known about the proteoglycans of connective tissue other than cartilage. Hence this paper is mainly concerned with cartilage proteoglycans. Proteoglycans are found throughout connective tissue, but those of cartilage have certain features that distinguish them from proteoglycans of ot...
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ژورنال
عنوان ژورنال: FEBS Letters
سال: 1972
ISSN: 0014-5793
DOI: 10.1016/0014-5793(72)80606-9